Autophosphoryiation of Rat Liver Type II cAMP-Dependent Protein Kinase
نویسندگان
چکیده
منابع مشابه
Subcellular Localization of the Type II CAMP-Dependent Protein Kinase
Hormone-receptor interactions generate signals that trigger protein kinase-catalyzed phosphorylation events (12). The action of 30 or more catecholamine and peptide hormones, as well as some prostaglandins, proceeds through parallel pathways that elevate intracellular adenosine 3’,5’-cyclic monophosphate (CAMP) and lead to activation of the CAMP-dependent protein kinase (PKA). An apparent parad...
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We have investigated the effect of theophylline on the kinetics of the catalytic subunit of protein kinase and related factors in lung tissue. The results show that the point of highest concentration of the C subunit of protein kinase which is active in casein phosphorylation is at 3h of incubation time, but in the presence of 100 Ilg/ InL and 10µg/mL theophylline, this is shifted to I.S an...
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To elucidate the role of cAMP and different cAMP-dependent protein kinases (PKA; A-kinase) in lung cell proliferation, we investigated rat alveolar type 2 cell proliferation in relation to activation or inhibition of PKA and PKA regulatory subunits (RIIalpha and RIalpha). Both the number of proliferating type 2 cells and the level of different regulatory subunits varied during 7 days of culture...
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Malignant transformation of cells is associated with enhanced proliferation and alterations in cAMP-dependent protein kinase (PKA) activity. To investigate the role of PKA in normal colonic cell proliferation, PKA was characterized in rat colonic mucosa. In addition, rats were fed diets containing different fats (corn oil, fish oil) and fibers (pectin, cellulose, fiber free) to elicit varying l...
متن کاملthe effect of theophylline on the kinetics of camp-dependent protein kinase catalytic subunit, camp, protein kinase inhibitor and their relationship in lung tissue
we have investigated the effect of theophylline on the kinetics of the catalytic subunit of protein kinase and related factors in lung tissue. the results show that the point of highest concentration of the c subunit of protein kinase which is active in casein phosphorylation is at 3h of incubation time, but in the presence of 100 ilg/ inl and 10µg/ml theophylline, this is shifted to i.s and 2....
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ژورنال
عنوان ژورنال: Molecular Endocrinology
سال: 1989
ISSN: 0888-8809,1944-9917
DOI: 10.1210/mend-3-11-1815